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Catalyst evidence graph

Findings on what compounds and supplements do in the body, with evidence strength, quote and paper.

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Install

mcp_config.json

{
  "mcpServers": {
    "ai-catalystproject-evidence-graph": {
      "url": "https://catalystproject.ai/mcp",
      "type": "streamable-http"
    }
  }
}

Documentation

Catalyst evidence graph — MCP server, plugins and extensions

Catalyst is a curated evidence graph of what compounds, supplements, nutrients and foods have been shown to do in the human body. This repository connects it to the assistants and editors people already use. The server itself is hosted; everything here only tells a client where it is.

Server: https://catalystproject.ai/mcp — MCP over Streamable HTTP, read-only, no account, no key. Registry name: ai.catalystproject/evidence-graph Setup for every client, the tool list and limits: https://catalystproject.ai/connect

What an assistant gets

  • Findings for a compound or an outcome. Every finding carries an evidence_strength — strong, moderate, limited, very_limited or insufficient — computed from the study behind it, never set by hand, plus the verbatim sentence it was drawn from, the paper, the population and dose, and a permalink to check it.
  • Relations from reference databases (targets, pathways, reactions), each labelled as a hypothesis rather than a reported result.

Evidence strength describes how well the evidence supports a finding. It is not a recommendation, and nothing here is medical advice. No tool returns a product, a price or a link to buy anything, and no tool ranks what to take.

Changed in 0.2.0 (ADR-0103): tool results report evidence_strength as a named level and never a letter, and get_findings takes an evidence_strength floor. The grade field and the grade argument are gone; a call that still sends grade gets an error naming the replacement.

Install

ClientHow
Claude (web, desktop)Settings → Connectors → Add custom connector → https://catalystproject.ai/mcp
ChatGPTDeveloper mode → add a custom app/connector with https://catalystproject.ai/mcp
Claude Code (plugin, adds the server and a skill for presenting evidence strength)/plugin marketplace add colorcatalyst/catalyst-mcp then /plugin install catalyst@catalyst
Claude Code (server only)claude mcp add --transport http catalyst https://catalystproject.ai/mcp
VS Code / GitHub CopilotThe Catalyst Evidence Graph extension (VSIX on the releases page), the one-click link on /connect, or .vscode/mcp.json below
CursorOne-click install, or ~/.cursor/mcp.json below
Gemini CLIgemini extensions install https://github.com/colorcatalyst/catalyst-mcp
Anything elsethe JSON below
{ "mcpServers": { "catalyst": { "url": "https://catalystproject.ai/mcp" } } }

VS Code's own file takes a slightly different shape:

{ "servers": { "catalyst": { "type": "http", "url": "https://catalystproject.ai/mcp" } } }

In this repository

PathWhat it is
server.jsonThe entry in the official MCP registry
.claude-plugin/marketplace.json, plugins/catalyst/A Claude Code plugin marketplace with one plugin: the server and an evidence-strength skill
gemini-extension.json, GEMINI.mdA Gemini CLI extension
vscode/A VS Code extension that registers the server with Copilot's agent mode

Privacy

The server stores no queries and has no accounts. Rate limits count calls per minute against the client's name and a keyed hash of the network address, never the address itself. Full notice: https://catalystproject.ai/privacy.

Contact

Questions, or something an assistant got wrong from this graph: hello@catalystproject.ai

The code in this repository is MIT-licensed. The graph's content carries the terms on https://catalystproject.ai/terms and per-source licences on https://catalystproject.ai/attribution.

Sourced from the repository README.

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